Hello!

This week we watched a video on transcription factors, which are "proteins that bind to DNA and encourages RNA polymerase to bind to start transcription." Some transcription factors also prevent binding.

I also used JGI/IGM to pick 3 random bacteria species. The names are in bold-face, and I also have each of their ecosystem details... Which are all exactly the same!

 Neisseria meningitidis:  Host-associated; Human; Digestive system; Large intestine; Fecal

Helicobacter pyloriHost-associated; Human; Digestive system; Large intestine; Fecal

Streptococcus pneumoniae: Host-associated; Human; Digestive system; Large intestine; Fecal


Afterwards, I also looked up transcription factors:



The above picture shows that this transcription factor is involved in negative gene regulation. Negative regulation is when a gene is prevented from being expressed.

Here's additional details on this transcription factor:

Motif structure: Inverted repeat

G/C content: 69.23%

Regulatory Mode:

  •  Activation:    0%
  •  Repression:   100%
  •  Dual:   0%
  •  Not Specified:   0%.

TF Conformation:

  •  Monomer:   0%
  •  Dimer:   0%
  • Tetramer:   100%
  • Other:   0%
  • Not Specified:   0%

Binding site type:

  • Motif-associated:   1
  • Variable-motif-associated:   0
  • Non-motif-associated:   0



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