Semester 3: 9/5/2020

Hello, all 😙
My protein this semester is CH—CH-CHIA! Just kidding... sort of. 
It’s called UniProtKB-Q9BZP6 (CHIA_HUMAN) or (in English) acidic mammalian chitinase, and the gene is CHIA. 

It’s sequence length is 476.
The mass is 52,271 Da.

It has several functions it is involved in. Though I have listed all of the functions UniProt provides, I compressed each one quite a lot ☺️ 

-Degrades chitin and chitriose.
-Th2 immune response.
-IL-13 inflammation response.
-Chemokine production.
-Protects lung epithelial cells from apoptosis.
-Phosphorylation pf AKT1.
-May help in defense against nematodes, fungi, and other (unlisted) pathogens.

This is a little summary of what I have so far. More information to come! 

Comments

  1. JJ MunozSeptember 6, 2020 at 2:38 PM

    It will be interesting to see the difference between CHIA and CHIT1. Some of their functions are similar.

    ReplyDelete
  2. Cam8706September 8, 2020 at 4:01 PM

    Awesome job looking forward to seeing more information about your protein

    ReplyDelete
  3. Anthony LunaSeptember 9, 2020 at 9:43 PM

    Kathleen,

    I found it particularly interesting that this protein functions in protecting lung cells from apoptosis. I thought chitinase would have been unique to fungi. However, this assumption was because I recall learning of chitin in gen. bio 2.

    ReplyDelete
  4. KaylynnSeptember 10, 2020 at 6:45 PM

    Awesome job on the comments guys. Science is all about communication. Keep it going!

    Chad

    ReplyDelete

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